ASUS Unleashes GB300-Powered Desktop Supercomputer

ASUS has quietly introduced one of the most powerful desktop-class AI machines to date: the ExpertCenter Pro ET900N E3, a compact supercomputer packed with NVIDIA’s GB300 Blackwell Superchip. This system, which looks like a standard desktop PC, leverages enterprise-grade architecture to deliver an astonishing 20 PFLOPS of AI performance, bringing unprecedented compute capabilities right to your desk.

Full product details are now available on ASUS’s official page, where the company highlights the desktop’s disruptive form factor and capabilities that rival traditional data center hardware.

At the heart of this AI powerhouse lies the GB300 platform, a combination of NVIDIA’s Grace CPU and Blackwell B300 GPU, delivering specialized performance for large language models (LLMs), deep learning training, and scientific workloads. The chip is supported by a staggering 784 GB of coherent memory, comprised of 496 GB LPDDR5X surrounding the Grace CPU and 288 GB of HBM3E for the GPU. Together, these components form a memory architecture capable of handling the most memory-hungry AI operations with fluidity and speed.

For data-intensive workflows and networking, the ET900N E3 incorporates ConnectX-8 SuperNIC, offering 800 GB/s networking bandwidth. It also runs on NVIDIA’s DGX OS, further solidifying its focus on AI and HPC (High-Performance Computing) environments.

Despite its data center-level specs, ASUS has engineered this system with modularity and expansion in mind. The system board includes three PCIe x16 slots, making it capable of multi-GPU expansion or adding custom hardware accelerators. Additionally, three M.2 NVMe SSD slots support fast storage configurations. Power delivery is handled via three onboard 16-pin connectors, offering a maximum of 1800W, ensuring enough headroom for heavy workloads and GPU scalability.

While the desktop includes a single GB300 Superchip, ASUS also referenced the GB300 NVL72, NVIDIA's colossal rack-mounted solution with 72 Blackwell Ultra GPUs and 36 Grace CPUs, delivering up to 1.4 ExaFLOPS and 40TB of coherent memory. That configuration is clearly reserved for server-grade infrastructure, but the ET900N E3 is tailored for businesses that want workstation-class power at their fingertips.

For organizations requiring scalable performance but without the space or complexity of server rooms, ASUS also offers the ExpertCenter Pro ET900N G3, another workstation built to support intensive data processing and AI tasks. You can explore more about that model on ASUS’s G3 workstation page.

Pricing has yet to be revealed, but considering the cutting-edge components and performance tier, it's safe to assume the system will come with a high-end price tag, likely running into several thousand dollars.

ASUS’s ExpertCenter Pro ET900N E3 marks a pivotal moment in bringing supercomputer-grade AI performance to the desktop form factor, opening new avenues for developers, researchers, and enterprises seeking on-site high-performance computing.


Would you want 20 PFLOPS of AI compute power on your desk, or is it too much for the average user? Let us know your thoughts below.

Angel Morales

Founder and lead writer at Duck-IT Tech News, and dedicated to delivering the latest news, reviews, and insights in the world of technology, gaming, and AI. With experience in the tech and business sectors, combining a deep passion for technology with a talent for clear and engaging writing

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